Joseph P. Errico,Francis R. Amato,Steven M. Mendez,Hecheng Hu,Bruce J. Simon
申请号：
US16854034
公开号：
US20200246617A1
申请日:
2020.04.21
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Systems and methods for reducing or inhibiting an inflammatory response in a patient include a source of energy and one or more electrodes coupled to the source of energy and positionable near a vagus nerve of the patient to deliver the electrical impulse to the vagus nerve. The electrical impulse is sufficient to either inhibit a release of a pro-inflammatory cytokine, such as TNF-alpha, or increase an anti-inflammatory competence of a cytokine, such as TGF-beta, in the patient, thereby inhibiting the inflammatory response. The electrical impulse may be delivered transcutaneously and non-invasively through an outer skin surface of the patient to the vagus nerve.
