PROBLEM TO BE SOLVED: To provide a pharmaceutical composition used for treatment of proteinuric diseases.SOLUTION: A pharmaceutical of treating proteinuric diseases comprises an &alpha；v&bgr；3 integrin inhibitor which is an &alpha；v&bgr；3 monoclonal antibody, a peptide which comprises an RGD binding sequence (cyclo-[Arg-Gly-Asp-D-Phe-Val]), or a compound represented by the following formula.【課題】蛋白尿症の治療に使用するための医薬組成物の提供。【解決手段】αｖβ３モノクローナル抗体か、ＲＧＤ結合配列を含むペプド（環状［Ａｒｇ－Ｇｌｙ－Ａｓｐ－Ｄ－Ｐｈｅ－Ｖａｌ］）か、以下の式で表わされる化合物か、であるαｖβ３インテグリン阻害剤を含む蛋白尿症治療医薬。【選択図】なし
