SABIN, Leah,SCHOENHERR, Christopher,ECONOMIDES, Aris N.,KYRATSOUS, Christos,MURPHY, Andrew J.
申请号:
SG11201911614X
公开号:
SG11201911614XA
申请日:
2018.06.27
申请国别(地区):
SG
年份:
2020
代理人:
摘要:
Provided herein are compositions and methods for redirecting recombinant viral capsid particles via a specific protein:protein binding pair that forms an covalent, e.g., isopeptide, bond to display a targeting ligand on the capsid protein, wherein the targeting ligand specifically binds a cell surface marker expressed on the cell of interest.