KOMINOS, Dorothea,ZHANG, Jie,PRITSKER, Alla,DAVISON, Matthew,BAURIN, Nicolas,SUBRAMANIAN, Govindan,CHEN, Xin,LI, Han
申请号：
DK17179380
公开号：
DK3246339T3
申请日:
2013.03.15
申请国别(地区):
DK
年份:
2020
代理人:
摘要：
The disclosure provides antibodies that specifically bind to Kallidin or des-Arg10-Kallidin. The disclosure also provides pharmaceutical compositions, as well as nucleic acids encoding anti-Kallidin or des-Arg10-Kallidin antibodies, recombinant expression vectors and host cells for making such antibodies, or fragments thereof. Methods of using antibodies of the disclosure to modulate Kallidin or des-Arg10-Kallidin activity or detect Kallidin or des-Arg10-Kallidin or, either in vitro or in vivo, are also provided by the disclosure . The disclosure further provides methods of making antibodies that specifically bind to des-Arg 9 - Bradykinin and des-Arg 10 -Kallidin-like peptide.
