The present invention relates to a hybrid channels for an inhalation device, in particular to a hybrid channel with improved injection and Combination, it is used to inject and mix a liquid medicine and enters the air-flow stream in hybrid channel, therefore generates the aerosol sucked by a patient. One aspect of the invention is related to a hybrid channel for an inhalation device, including the import between inlet and outlet hole, one outlet opening, an and injection zone, wherein injection zone has a vertical central axis, wherein injection zone includes (a) a built-in sprayer, or (b) dismountable sprayer, or be suitable for receiving (c) component of a dismountable sprayer, wherein the effective cross sectional area of the hybrid channel in the plane for being transversely to the machine direction central axis one than injection zone upstream is smaller in injection zone.
