Nick VAN WIJK,Robert Johan Joseph HAGEMAN,Mehmet CANSEV
申请号：
US15115487
公开号：
US20170157164A1
申请日:
2015.02.02
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The invention pertains to the use of one or more of uridine and cytidine, or salts, phosphates, acyl derivatives or esters thereof in the manufacture of a composition for treating, preventing or reducing the risk of occurrence of white matter lesions, white matter hyperintensities (WMH), Leukoaraiosis or periventricular white matter disease in elderly not suffering from a neurodegenerative disorder, preferably non-demented elderly and elderly not suffering from Alzheimer's Disease. It was found that with the compositions according to the invention Nogo-A protein levels could be controlled, particularly suppressed or reduced.
