Genus Oncology, LLC; Inc.;Dana-Farber Cancer Institute;Dana-Farber Cancer Institute, Inc.
发明人:
Kufe, Donald W.,Kharbanda, Surender
申请号:
AU2009305550
公开号:
AU2009305550B2
申请日:
2009.10.16
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
The invention provides for peptides from the MUCl cytoplasmic domain and methods of use therefor. These peptides can inhibit MUCl oligomerization, thereby preventing tumor cell growth, inducing tumor cell apoptosis and necrosis of tumor tissue in vivo.