PROBLEM TO BE SOLVED: To provide compositions for treating heart disease that can improve cell engraftment rate and provide improved therapeutic effects, in cell transplantation therapy using a catheter.SOLUTION: Provided is a composition for treating heart disease used for cell transplantation therapy, administered by catheter, comprising cells and a bioactive substance carried on a sustained-release carrier, the bioactive substance having at least one function selected from a function of enhancing the differentiation ability of the cells into myocardium and/or blood vessels, a function to enhance the ability of cardiac fibrotic tissue to differentiate into myocardium and/or blood vessels, and a function to enhance the proliferative capacity of cardiac myocardial cells and/or vascular cells.SELECTED DRAWING: NoneCOPYRIGHT: (C)2020,JPO&INPIT【課題】カテーテルによる細胞移植療法において、細胞の生着率を向上させ、改善した治療効果をもたらすことができる、心疾患治療用組成物を提供する。【解決手段】細胞移植療法に用いられる心疾患治療用組成物であって、カテーテルによって投与され、細胞と、徐放性担体に担持された生物活性物質とを含み、前記生物活性物質が、前記細胞の心筋及び／又は血管への分化能を増強させる機能、心臓の線維化組織の心筋及び／又は血管への分化能を増強させる機能ならびに心臓の心筋細胞及び／又は血管細胞の増殖能を増強させる機能から選ばれる少なくとも１つの機能を有する、組成物。【選択図】なし
