A method of positioning a device for pedicle access includes securing a clip in an adjustable frame assembly and securing the device in the clip. The method also includes positioning the device at an initial position having a trajectory estimated to allow the device to penetrate a pedicle without damaging the nervous system, and determining whether the trajectory of the initial position is proper to avoid damage. Further, the method includes re-positioning the device to a new position if the trajectory of the initial position is not proper to avoid damage to the nervous system, and determining whether the trajectory of the new position is proper to avoid damage. The method also includes repeating the steps of re-positioning the device and determining whether the trajectory of the new position is proper as required until a proper trajectory is obtained.