An image processing device includes a special light image acquisition section that acquires an image including an object image that includes information in a specific wavelength band as a special light image, an attention area detection section that detects an attention area based on a feature quantity of each pixel of the special light image, a disappearance determination section that determines whether or not the attention area has disappeared from a display target area based on a detection result for the attention area, the display target area being an area displayed on an output section, a guide information generation section that generates guide information about the attention area that has disappeared based on a determination result of the disappearance determination section, and an output control section that controls output of information including the guide information generated by the guide information generation section.