#$%^&*AU2014101478A420150122.pdf#####ABSTRACT The present invention provides a method for treating a subject using intermittent hypoxia, the method comprising the steps of: exposing the subject to hypoxic air for a time period, measuring the heart rate variability of the subject, and altering the oxygen concentration in the hypoxic air and/or the time period for which the subject is exposed to the hypoxic air according to the measured heart rate variability. Also provided is a system for treating a subject using intermittent hypoxia, the system comprising: a gas delivery means configured to provide a hypoxic air, and a heart rate variability measuring means, an automated control means configured to control the oxygen concentration in the hypoxic air and/or the time period for which a subject is exposed to the hypoxic air according to the measured heart rate variability.12 1 28 14 ----0SUBJECT PULSE HYPOXIMATER 16 24IG 34