Methods for antihypertensive drug dosing by pharmacokinetic parameter determination. In one embodiment, the antihypertensive drug is olmesartan and the pharmacokinetic parameter is AUC. The methods are effective for treating hypertension.藉由藥物動力學參數測定給與抗高血壓藥物之劑量的方法。在一具體例中,該抗高血壓藥物是奧美沙坦,且該藥物動力學參數是AUC。該等方法是有效的用於治療高血壓。