An ultrasonic needle driver is provided. The driver includes a housing, an ultrasonic transducer mounted within the housing, a coupling mechanism operably connected to and extending distally from the ultrasonic transducer, and a tool assembly operably connected to the coupling mechanism. The tool assembly may be configured for selectively retaining a suture needle. The housing may include a handle assembly for actuating the tool assembly. The handle assembly may include a pair of handles. The handles are spaced apart from the housing when in a first position. The handles may be approximated toward the housing to actuate the tool assembly. The tool assembly may include a jaw member. The housing may be configured for operable engagement by a user and may define a substantially elongated body. The housing may define a pistol or pencil grip. The driver may also include an activation mechanism for activating the ultrasonic transducer. The driver may further include a control module integrally formed therewith.
