The Invention comprises a body, an actuator pivotally connected to the body, and a retractable needle adapted to provide fluid communication between a patient and a fluid collection tube, typically a blood collection tube, attachable to the device. A significant feature of the subject device is a retraction cavity disposed inside the actuator that is manually positionable to receive a portion of the needle retraction assembly following removal of the blood collection tube. Retraction is initiated by depressing the forwardly extending end of the actuator relative to the body, thereby causing a retainer clip to release the needle holder, after which the needle holder and a part of the needle are propelled into the retraction cavity by expansion of a compressed spring. The needle is thereby withdrawn from the patient and into the housing, reducing the likelihood of accidental needle sticks and preventing reuse of the device.