D'AMOUR, KEVIN ALLEN,KROON, EVERT,SCOTT, MICHAEL,MARTINSON, LAURA,MCGREEVY, CRAIG,DAMOUR, KEVIN ALLEN
申请号:
CA3042495
公开号:
CA3042495A1
申请日:
2016.11.10
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
Disclosed are devices and methods for transplanting cells, such as pancreatic endoderm cells, into a host. The devices include a non-woven fabric external to a cell-excluding membrane, and the non-woven fabric and/or cell-excluding membrane can be perforated. Treatment of the host with immunosuppressive reagents, required to inhibit allograft rejection due to perforations in the cell delivery device, does not compromise maturation or function of transplanted pancreatic endoderm cells.