The transdermal administration device of the present invention includes: a device body including a needle form body, which includes a plurality of microneedles formed on a surface thereof and is provided with a fluid passage hole through the front surface to a back surface thereof, and a medical fluid filling section for providing a medical fluid to the back surface of the needle form body a stratum corneum peeling system and a connection section for connecting the device body and the stratum corneum peeling system, where the stratum corneum peeling system is connected to the device body by the connection section such that the microneedles of the needle form body of the device body are positioned in an area of a skin surface in which a stratum corneum is peeled by the stratum corneum peeling system.