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Thermoprotected compositions and process for terminal steam sterilization of microparticle preparations
专利权人:
Awadhesh K. Mishra
发明人:
Awadhesh K. Mishra
申请号:
US09321766
公开号:
US08415329B1
申请日:
1999.05.28
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Compositions of submicron- to micron-sized particles of water-insoluble biologically active substances that are stabilized by thermoprotecting agents, can be terminally steam sterilized without any significant increase of mean particle size. These compositions display markedly reduced heat-induced coagulation, flocculation, or particle size growth during the terminal steam sterilization process.
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