Anders Jarstad,Anna Friis,Ulf Stáhl,Ann Gurell,Barbro Àgren,EmiIia Edström,Andrew Pickett,Ulf Stá,gren,Barbro À
申请号：
MOI001522
公开号：
MOI001522A
申请日:
2017.05.26
申请国别(地区):
MO
年份:
2018
代理人:
摘要：
The present invention relates to the stable liquid neurotoxin preparations for being free of animal protein, the neurotoxin preparation includes surfactant, amino acid (selected from tryptophan and tyrosine), buffer (including sodium ion, chloride ion and phosphate anion), the pH of the neurotoxin preparation stablizes 2 months between 5.5 and 8. These compositions are suitble to use what therapeutical uses, especially give patient with what to obtain desired therapeutic effect or cosmetic result. The invention further relates to the amino acid selected from tryptophan and tyrosine without animal origin protein liquid composition in protected protein matter neurotoxin exempt from what degradation purposes.本發明涉及不含動物蛋白質的穩定的液體神經毒素製劑，所述神經毒素製劑包含表面活性劑、氨基酸（選自色氨酸和酪氨酸）、緩衝液（包含鈉離子、氯離子和磷酸根離子），所述神經毒素製劑的pH在5 .5和8之間，並且穩定2個月。這些組合物適合用於治療用途，尤其是用於給予患者以獲得期望的治療效果或美容效果。本發明還涉及選自色氨酸和酪氨酸的氨基酸在不含動物來源的蛋白質的液體組合物中保護蛋白質神經毒素免於降解的用途。
