Robert Syndecombe Bower;Gina Diane Nicholas;Mark Francis Thomas;Carole Judith Berry;Monica Senna Salerno De Moura
发明人:
Robert Syndecombe Bower,Monica Senna Salerno De Moura,Gina Diane Nicholas,Mark Francis Thomas,Carole Judith Berry
申请号:
US13499566
公开号:
US20130065820A1
申请日:
2010.09.29
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to novel synthetic myostatin antagonists, comprising a synthetic mature myostatin peptide, wherein the peptide comprises at least two cysteine residues at positions 281 and 282 which are forced to bond and form a disulfide bond or a functional variant or fragment thereof and are useful in the treatment of myostatin related disorders.