A synchronization method for single event list type data in PET imaging. The method comprises the steps of: acquiring single event list type data of each independently operating detection module calculating the probability density of time intervals among single events occurring in each detection module, and setting an initial parameter using iterative peak searching and graded time window peak searching to determine the difference value between the detection starting times of the detection modules and using the above-mentioned time difference value to conduct synchronization correction and coincidence discrimination on the single event data in the detection module. A synchronization system for single event list type data in PET imaging, comprising: a data acquisition and frequency difference compensation module (100), an initial parameter setting module (200), a coarse time scale coincidence module (300), a fine time scale coincidence module (400) and a data synchronization correction and coincidence discrimination module (500). The present disclosure can effectively and accurately complete the synchronization of single event list type data, simplify the hardware design of the system, and improve the flexibility, expansibility and adaptability of the system.
