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Nanofibrous scaffold comprising immobilized cells
专利权人:
Glenn Gaudette
发明人:
Glenn Gaudette,Matthew D. Phaneuf,Syed Ali,Brian Almeida,Helena Alfonzo,Katie Flynn
申请号:
US12954829
公开号:
US08691543B2
申请日:
2010.11.26
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The invention is directed to a device and method to prevent migration of Human Mesenchymal Stem Cells (hMSCs) from a delivery site while allowing communication between the stem cells and native cardiomyocytes. The device is characterized by scaffold pore size, fiber diameter and biomaterial selection. The invention includes a two part polyurethane scaffold that prevents migration of stem cells, allows gap junction formation through pores and is packaged for minimally invasive delivery.
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