Emmanuelle BOUISSOU-CADIO,Gaelle GENDRONNEAU,Francois LEJEUNE,Irina BERLIN
申请号:
US15831769
公开号:
US20180180629A1
申请日:
2017.12.05
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Disclosed are methods for screening for candidate compounds for hydrating the skin. The compounds selected according to the methods disclosed therein stimulate the intra-cellular amount and/or activity of TonEBP in keratinocytes. Preferably, the selected compounds induce a stimulation of at least 20%, preferably at least 50%, preferably at least 100% of the activity and/or intra-cellular amount of TonEBP.