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APOPTOSIS-TARGETING NANOPARTICLES
专利权人:
发明人:
申请号:
EP12829002.0
公开号:
EP2750662A1
申请日:
2012.08.31
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
Nanoparticles include a core and one or more targeting moieties, as well as one or more contrast agents or one or more therapeutic agents. The contrast agents or therapeutic agents may be contained or embedded within the core. If the nanoparticle includes therapeutic agents, the agents are preferably released from the core at a desired rate. The core may be biodegradable and may release the agents as the core is degraded or eroded. The targeting moieties preferably extend outwardly from the core so that they are available for interaction with cellular components, which interactions will target the nanoparticles to the appropriate cells, such as apoptotic cells organelles, such as mitochondria or the like. The targeting moieties may be tethered to the core or components that interact with the core.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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