The invention relates to a hysteroscopic technique and specific instrument, applicator or device inserter, to insert a frameless, anchored device for intrauterine and intratubal delivery of bioactive substances for long-acting contraception and gynecological treatment. This is realized by the invention of a specially designed inserter allowing the passage through the narrow working channel of a specially designed hysteroscope for the precise insertion of an anchoring means, a non-biodegradable or biodegradable anchoring knot, or a hook, under direct vision in the fundal wall of the uterus, and to which a biological active component is attached which consists of a copper, copper-silver or another metallic ion-releasing agent, or a drug-eluting system for the release of a hormone or hormone-antagonist or other substance, active in the uterus as well as in the oviducts, and which can be hand-fixed to the hysteroscope by means of a thumbpiece fixed to the inserter tube to allow safe and controlled insertion.