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LIPIDE CATIONIQUE
专利权人:
NOF CORPORATION;NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
发明人:
NAKAI, YUTA,TANGE, KOTA,AKITA, HIDETAKA,HARASHIMA, HIDEYOSHI,TOGASHI, RYOHEI,MIURA, NAOYA,MAETA, MIO
申请号:
CA2975371
公开号:
CA2975371A1
申请日:
2016.01.29
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The purpose of the present invention is to provide a cationic lipid that can be used as a nucleic acid delivery carrier, a lipid membrane structure in which the cationic lipid is used, a nucleic-acid-introducing agent in which the cationic lipid is used, and a method for achieving nucleic acid introduction using the nucleic-acid-introducing agent containing the cationic lipid. The lipid membrane structure containing the cationic lipid represented by formula (1) (in the formula, each of the symbols is as defined in the specification) has exceptional stability in the blood and tumor accumulation properties. The nucleic-acid-introducing agent in which this cationic lipid is used makes it possible to achieve high nucleic acid delivery efficiency of a nucleic acid to be delivered into the cytoplasm.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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