Disclosed is a composition for cleaning medical or dental instruments including a protease and a biostatically effective phenoxy alcohol at a concentration below its MIC against Pseudomonas aeruginosa (ATCC 15442), wherein the composition is effective to reduce a 6 log concentration of Pseudomonas aeruginosa (ATCC 15442) by at least a log concentration within 4 hours, the composition further comprising boron or a boron compound.
