Matthew David Butts,Robert Edgar Colborn,Peter John Bonitatibus, Jr.,Andrew Soliz Torres
申请号：
US15187115
公开号：
US09585974B2
申请日:
2016.06.20
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Compositions of nanoparticles functionalized with at least one zwitterionic moiety, methods for making a plurality of nanoparticles, and methods of their use as diagnostic agents are provided. The nanoparticles have characteristics that result in minimal retention of the particles in the body compared to other nanoparticles. The nanoparticle comprising a nanoparticulate transition metal oxide covalently functionalized with a silane-functionalized non-targeting zwitterionic moiety.
