The present invention provides the composition of prevention or treatment with what itching. The prevention of the itching and/or the characteristic of therapeutic composition contain the substance from Acacia bark in what.本發明提供用於搔癢的預防或治療的組合物。該搔癢的預防和/或治療用組合物的特徵在於含有來自金合歡屬樹皮的物質。