Normington, Karl D.,Westphal, Christopher H.,Milne, Jill,Fujii, Jennifer,Dipp, Michelle,Milburn, Michael,Elliot, Peter
申请号:
AU2006204699
公开号:
AU2006204699B2
申请日:
2006.01.13
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
Provided herein are methods and compositions for treating or preventing neurodegenerativedisorders or blood coagulation disorders. Methods may comprise modulatingthe activity or level of a sirtuin, such as SIRTl or Sir2. Exemplary methods comprisecontacting a cell with a sirtuin activating compound, such as a flavone, stilbene,flavanone, isoflavone, catechin, chalcone, tannin or anthocyanidin; or aninhibitory compound, such as nicotinamide.