A small animal anesthesia system is provided, including a compressor, an anesthetizing gas generator and an anesthesia platform. The compressor has a first outlet and a first intake. The anesthetizing gas generator has a second outlet and a second intake. The first outlet of the compressor is connected to the second intake of the anesthetizing gas generator to supply gas, so that an anesthetizing gas is generated. The anesthesia platform includes a bearing plate, an anesthetic mask and a first anesthesia chamber. The anesthetic mask is configured to cover the face of the small animal, and connected to the second outlet of the anesthetizing gas generator, such that the small animal is anesthetized by the anesthetizing gas generated by the anesthetizing gas generator. The first anesthesia chamber is disposed on the bearing plate, and connected to the first intake of the compressor to recycle the anesthetizing gas.