Daniella Licht;Ioana Lovinger;Aharon M. Eyal;Muhammad Safadi;Tomas Fristedt;Karl Jansson
发明人:
Muhammad Safadi,Daniella Licht,Ioana Lovinger,Aharon M. Eyal,Tomas Fristedt,Karl Jansson
申请号：
US12317104
公开号：
US08178127B2
申请日:
2008.12.19
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The subject invention provides a pharmaceutical composition comprising N-ethyl-N-phenyl-1,2,-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxoquinoline-3-carboxamide or the salt thereof； a pharmaceutically acceptable carrier； and not more than 0.5% w/w relative to N-ethyl-N-phenyl-1,2,-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxoquinoline-3-carboxamide of 2-Chloro-6-(1-ethyl-N-methyl-2-oxoindoline-3-carboxamido)benzoic acid, 1H,3H-spiro[5-chloro-1-methylquinoline-2,4-dione-3,3′-[1]ethylindolin-[2]-one], or 5-Chloro-N-ethyl-3-hydroxy-1-methyl-2,4-dioxo-N-phenyl-1,2,3,4-tetrahydro-quinoline-3-carboxamide.
