A syringe with high safety in use having a syringe body adapted to accommodate slidingly a plunger. The syringe body has a protruding end that is adapted to allow the mating of a base end of a needle. The syringe further includes elements for removing the needle and/or a cap interposed between the syringe body and the base end of the needle. The needle removal elements are adapted to be moved in a rotary direction for removal of the needle and/or the cap.
