A device for tissue sampling and grafting has a handle (2), to whose end is fixed a coupling (4), a needle (6) fixed to the coupling. The device also includes a piston (3) connected to a pin (7). The piston and pin translate between an external condition (A), wherein a tip (73) of the in protrudes beyond the needle, and an internal condition (B), wherein the tip is retracted inside the needle. The device also includes a tip (5), having a truncated free end (51) that can be sharpened, constrained in a roto-translating way to the coupling, placed co-axially and externally to the needle and moved between a retracted condition (C) and an advanced condition.
