(4-hidroxi-2-fenil-1,3-tiazol-5-il)-metanon származékok, mint TRPM8 antagonisták

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专利权人:

Dompe farmaceutici S.p.A.

发明人:

ARAMINI, Andrea,BIANCHINI, Gianluca,LILLINI, Samuele

申请号：

HUE16823231

公开号：

HUE046284T2

申请日:

2016.12.16

申请国别(地区):

HU

年份:

2020

代理人:

摘要：

The invention relates to compounds acting as antagonists of Transient Receptor Potential cation channel subfamily M member 8 (TRPM8), and having formula (I): Said compounds are useful in the treatment of diseases associated with activity of TRPM8 such as pain, ischaemia, neurodegeneration, stroke, psychiatric disorders, itch, irritable bowel diseases, cold-induced and/or exacerbated- respiratory disorders, urological disorders, corneal disordes associated to disturbances in the production of the tears and/or altered blinking such as epiphora and dry eye disease.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/