Emory University;Children's Healthcare of Atlanta, Inc.
发明人:
Jacques Galipeau,Jiusheng Deng
申请号:
US15491777
公开号:
US20170226173A1
申请日:
2017.04.19
申请国别(地区):
US
年份:
2017
代理人:
摘要:
In certain embodiments, this disclosure relates to conjugates comprising a polypeptide of GM-CSF and a polypeptide IL-4. Typically, the GM-CSF and IL-4 are connected by a linker, e.g., polypeptide. In certain embodiments, the disclosure relates to isolated nucleic acids encoding these polypeptide conjugates, vectors comprising nucleic acid encoding polypeptide conjugates, and protein expression systems comprising these vectors such as infectious viral particles and host cells comprising such nucleic acids.