ZHANG, LIANGFANG,FANG, RONNIE HONGBO,HU, CHE-MING (JACK),COPP, JONATHAN
申请号：
CA2873404
公开号：
CA2873404A1
申请日:
2012.05.24
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
Provided are nanoparticles, method of using and making thereof. The invention nanoparticle comprises a) an inner core comprising a non-cellular material； and b) an outer surface comprising a cellular membrane derived from a cell or a membrane derived from a virus. Medicament delivery systems or pharmaceutical compositions comprising the inventive nanoparticles are also provided. The present invention further provides immunogenic compositions comprising the inventive nanoparticles, and methods of use the inventive immunogenic compositions for eliciting an immune response and for treating or preventing disease or condition, such as neoplasm or cancer, or disease or conditions associated with cell membrane inserting toxin. Vaccines comprising the immunogenic composition comprising the nanoparticles of the present invention are also provided.
