ISHINO, TETSUYA,PALANKI, MOORTHY SITHARAMAIAH SURIYANARAYANA,VIOLAND, BERNARD NORMAN,DAS, TAPAN KANTI,HODGE, TAMARA SHAFER,PARSONS, ERIN KRISTEN,LEVIN, NANCY JANE
申请号:
TW100140134
公开号:
TW201233685A
申请日:
2011.11.03
申请国别(地区):
TW
年份:
2012
代理人:
摘要:
The present invention provides a FGF21 molecule covalently attached to the combining site of an antibody via a linker, wherein the linker is covalently attached to the side chain of a linking residue within FGF21. Various uses of the compounds are provided, including methods to prevent or treat diabetes or diabetes-related conditions.