Medical pressure therapy can be used on a patient having undergone treatment to reopen an arterial obstruction, such as a stenosis or occlusion. The medical pressure therapy can establish and maintain persistently good distal runoff. The can help ensure the patency of the region having undergone the treatment procedure. In some examples, the technique involves enclosing at least a portion of a limb of a patient on which an obstruction treatment procedure has been performed in an enclosure such that the portion of the limb is sealed from external conditions. The technique further involves alternately applying a negative pressure within the enclosure and releasing the negative pressure from within the enclosure, thereby increasing a volume and velocity of blood flowing past a region of the blood vessel previously-obstructed and thereby increasing distal runoff.
