GRONER, BERND, PROF. DR.,BORGHOUTS-HEINZ, CORINA, DR.
申请号:
EP11006391
公开号:
EP2392585A3
申请日:
2007.10.17
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
The present invention relates to scaffold proteins for recombinant peptide aptamers, especially to a modified variant of human thioredoxin, and to the aptamers themselves, especially apatamers binding to the transcription factor Stat3. The invention furthermore relates to Fusion Proteins of the scaffold protein and the aptamer, nucleic acids coding for these peptides or proteins, medicaments comprising same and their uses, especially in cancer therapy.