Phil Morgan;Mir A. Imran;Lu Wang;Joel M. Harris;Mir Hashim;Sanjay Patel
发明人:
Mir A. Imran,Mir Hashim,Lu Wang,Sanjay Patel,Joel M. Harris,Phil Morgan
申请号:
US13338210
公开号:
US20120177700A1
申请日:
2011.12.27
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Embodiments of the invention provide nanonized iron compositions for treatment of iron deficiency such as iron deficiency anemia. Many embodiments provide nanonized iron compositions which are sized to minimize adverse reaction such as immune response, adverse GI reaction and allergic reaction to iron compound included in the composition. The nanonized iron compositions can be used in a variety of drug delivery forms, including an oral dosage form, a transdermal patch, in an intravenous solution or in a dialysate for treatment of a patient with chronic kidney disease (CKD). Embodiments of the invention also provide methods of using the nanonized iron compositions for the treatment of iron deficiency in a patient in need thereof including patients with iron deficiency anemia and CKD.