YAN, JIAN,SLAGER, ANNA,GARMAN, BRADLEY,COOCH, NEIL
申请号：
CA3083532
公开号：
CA3083532A1
申请日:
2018.12.13
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
Disclosed herein are nucleic acid molecules comprising one or more nucleic acid sequences that encode a mutated consensus PRAME antigen. Vectors, compositions, and vaccines comprising one or more nucleic acid sequences that encode a mutated consensus PRAME antigen are disclosed. Methods of treating a subject with a PRAME-expressing tumor and methods of preventing a PRAME-expressing tumor are disclosed. Mutated consensus PRAME antigen is disclosed.
