Okinawa Institute of Science and Technology School Corporation
发明人:
申请号：
EP13846040.7
公开号：
EP2888268B1
申请日:
2013.10.04
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
Disclosed is a compound of formula I: wherein R1?, R2?, R3?, R4?, R5?, n and m are defined herein. The compound of formula I is prepared by a concise, catalytic enantioselective formal hetero-Diels-Alder (hDA) reactions of enones with isatins and is useful for making pharmaceutical composition for the treatment of proliferative diseases.
