The Board of Trustees of the Leland Stanford Junio Junior University
发明人:
Karl Deisseroth,Feng Zhang,David J. Mishelevich,M. Bret Schneider
申请号：
US16041647
公开号：
US20180326221A1
申请日:
2018.07.20
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Stimulation of target cells using light, e.g., in vivo, is implemented using a variety of methods and devices. In one example, embodiments involve methods for stimulating target cells using a photosensitive protein that allows the target cells to be stimulated in response to light. In another specific example embodiment, target cells are stimulated using an implantable arrangement. The arrangement includes an electrical light-generation means for generating light and a biological portion. The biological portion has a photosensitive bio-molecular arrangement that responds to the generated light by stimulating target cells in vivo. Other aspects and embodiments are directed to systems and methods for screening chemicals based screening chemicals to identify their effects on cell membrane ion channels and pumps, and to systems and methods for controlling an action potential of neuron (e.g., in vivo and in vitro environments).
