A blade exchange device may be used to remove or install a blade on a medical or surgical instrument such as a dermatome. The blade exchange device generally includes a base portion and a blade engaging portion that engages the blade being removed or installed. The blade exchange device may be used in a system that also includes a magnetic tool for coupling and moving the blades that are removed or installed. The blade exchange device, system and method may be used, for example, with commercially available dermatome instruments such as the type known as the Goulian-Weck knife.
