PROCEDE D'OBTENTION D'UN MATERIAU ACTIVE PAR GENE SOLIDE OPTIMISE, METHODE DE PREPARATION D'UNE STRUCTURE SOLIDE, MATERIAU ACTIVE PAR GENE SOLIDE OPTIMISE SERVANT A LA REGENERATION DES TISSUS
DEEV, ROMAN VADIMOVICH,ISAEV, ARTUR ALEKSANDROVICH,BOZO, ILYA YADIGEROVICH,KOMLEV, VLADIMIR SERGEEVICH
申请号:
CA3039118
公开号:
CA3039118A1
申请日:
2017.06.27
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The invention relates to medicine and veterinary science, and describes methods of producing optimized osteoplastic materials, characterized by a highly accurate dose of nucleic acids, more effective release dynamics of gene constructs from the structure of a carrier matrix, and an increased level of transfection of cells of the recipient bed by a biologically active substance. The first method relates to gene constructs, and enables same to be divided into two fractions which more effectively stimulate a repair process. The second method relates to functionalization of carrier matrices by complexing agents. Furthermore, a method is disclosed for producing sterile medical products from optimized gene-activated materials.