The Broad Institute, Inc.;The Brigham and Women's Hospital, Inc.;Massachusetts Institute of Technology
发明人:
申请号：
EP16795490.8
公开号：
EP3368689B1
申请日:
2016.10.28
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
The present invention provides markers, marker signatures and molecular targets that correlate with dysfunction of immune cells and are advantageously independent of the immune cell activation status. The present markers, marker signatures and molecular targets provide for new ways to evaluate and modulate immune responses. Therapeutic methods are also provided to treat a patient in need thereof who would benefit from an increased immune response.
