KINGS COLLEGE HOSPITAL NHS FOUNDATION TRUST;KING'S COLLEGE HOSPITAL NHS FOUNDATION TRUST;IBRAHIM MOHAMMAD
发明人:
申请号:
IL21973512
公开号:
IL219735D0
申请日:
2012.05.10
申请国别(地区):
IL
年份:
2012
代理人:
摘要:
This invention relates to a therapeutic molecule capable of suppressing an immune response against an organ or tissue transplantation in a patient. In particular, the invention relates to a conjugate comprising a first portion connected to a second portion, wherein the first portion binds to an MHC Class I molecule and the second portion has HLA-G activity. This conjugate may be used as a medicament to modulate immune responses and induce immunological tolerance specific to allogenic MHC complexes.