Marco MORRA,Clara CASSINELLI,Giorgio IVIGLIA,Elisa TORRE
申请号：
US16631393
公开号：
US20200215225A1
申请日:
2018.07.02
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Implant devices are coated with biologically active compounds, in particular with plant extracts from vinification residues. The implant devices are bone implants, and in particular dental implants. A method for functionalizing a surface of an implant device is includes the steps of a) optionally, treating the surface of the implant device with air, oxygen, argon, nitrogen plasma, and plasma capable of removing the surface layer of hydrocarbon contamination, b) treating the surface of the implant with an amine substrate, c) treating the surface of the implant resulting from step b), alternatively with a marcs extract, and drying the functionalized surface, or by co-adsorbing a marcs extract and hyaluronic acid, and drying the functionalized surface, or by adsorbing hyaluronic acid and post-adsorbing a marcs extract, and drying of the functionalized surface.
