A bioadhesive strip includes material that is removable or dissolvable in the oral cavity and adheres to the mucosal tissue of a person's oral cavity, with preferred embodiments including a specially textured surface on at least the outer side of an adhesive strip that faces away from the mucosal tissue to which it is attached and that has anti-microbial characteristics, bioluminescent expressions, etc. and a surface topography that resists bioadhesion of undesired bacteria that are typically present in a human's mouth. Methods of using the bioadhesive strip include treating snoring, sore throat conditions, GERD, NAFLD, Alzheimer's Disease, cachexia and migraines.