Chi-Huey Wong,Ming-Daw Tsai,Ying-Ta Wu,Yih-Shyun E. Cheng,Yu-Hou Chen,Yu-Fang Shen
申请号：
US13567355
公开号：
US20130040952A1
申请日:
2012.08.06
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Methods for identifying agents capable of disrupting a salt bridge in an influenza A virus nucleoprotein corresponding to the E339 . . . R416 salt bridge in SEQ ID NO:1, and thus the trimerization of the NP protein and uses of such agents, e.g., small molecules and peptides, for inhibiting influenza virus replication and treating infection caused by influenza virus.
